ALGSA NEWS2018-04-26T22:19:34+00:00
  • ALGSA Gala of Dreams

    The ALGSA Annual Gala - The Dawn of a Dream - took place at the end of June. We had a great time, and we hope you enjoy viewing some pictures from the event.

  • Building Better Bile Ducts Could Help ALGS Patients

    The bile ducts form a network of tubes within the liver and transfer bile produced in the liver to the bowel. In biliary disorders, this transport system fails, leading to the accumulation of toxic bile in the liver, damage, and permanent scarring (cirrhosis), which can ultimately be treated only through liver transplantation. Indeed, bile duct diseases (cholangiopathies) are the leading disorder treated (70%) by pediatric liver transplantation and account for a third of adult transplanted livers.

  • Binh Wagner Gets Donated Liver

    Michael and Johanne Wagner can’t express their gratitude enough. The couple from Kingston, Ont., broke down in tears Tuesday as they thanked an anonymous donor who made it possible for the second of their twin daughters to receive a life-saving liver transplant.

  • Children with Alagille Syndrome have malformed bile ducts

    Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

  • ITCH study shows reduction in pruritus in Alagille syndrome

    In a dose-varied study of maralixibat, patients’ caregivers reported trends toward pruritis relief while the drug also demonstrated safety, according to a presenter at The Liver Meeting 2017.

  • Identification of Key Mutation in Alagille Syndrome Offers Hope of New Treatment

    A RARE but potentially life-threatening genetic disorder, known as Alagille syndrome, is associated with chronic liver and heart problems in children. Little is understood regarding how the disease develops, and symptoms are currently treated separately.


“Mobilizing resources, facilitating connections, promoting unity, and advocating for a cure to inspire, empower, and enrich the lives of people affected by Alagille Syndrome.”